121 10 cover Kitamura A, Maekawa Y, Uehara H, Izumi K, Kawachi I, Nishizawa M, Toyoshima Y, Takahashi H, Standley DM, Tanaka K, Hamazaki J, Murata S, Obara K, Toyoshima I, Yasutomo K.
A mutation in the immunoproteasome subunit PSMB8 causes autoinflammation and lipodystrophy in humans. 

J Clin Invest 121:4150–4160 (2011)

In this issue
Mutation-mechanism-disease
J Clin Invest 121:3765 (2011)


 5.cover source Xu M, Morishima N, Mizoguchi I, Chiba Y, Fujita K, Kuroda M, Iwakura Y, Cua DJ, Yasutomo K, Mizuguchi J, Yoshimoto T.
Regulation of the development of acute hepatitis by IL-23 through IL-22 and IL-17 production.

Eur J Immunol 41:2828-2839 (2011)

123 Okamoto M, Takeda K, Lucas JJ, Joetham A, Yasutomo K, Gelfand EW.
Low-dose lipopolysaccharide affects lung allergic responses by regulating Jagged1 expression on antigen-pulsed dendritic cells. 

Int Arch Allergy Immunol 157:65-72 (2011)

m cover Kuwahara T, Ogura Y, Oshima K, Kurokawa K, Ooka T, Hirakawa H, Itoh T, Nakayama-Imaohji H, Ichimura M, Itoh K, Ishifune C, Maekawa Y, Yasutomo K, Hattori M, Hayashi T.
The Lifestyle of the Segmented Filamentous Bacterium: A Non-Culturable Gut-Associated Immunostimulating Microbe Inferred by Whole-Genome Sequencing. 

DNA Res 18:291-303 (2011)

eji Ishifune C, Maekawa Y, Nishida J, Kitamura A, Tanigaki K, Yagita H, Yasutomo K.
Notch signaling regulates the development of a novel type of Thy1-expressing dendritic cell in the thymus.
Eur J Immunol 41:1309-20 (2011) 

1 Sakata-Yanagimoto M, Sakai T, Miyake Y, Saito T, Maruyama H, Morishita Y, Nakagami-Yamaguchi E, Kumano K, Yagita H, Fukayama M, Ogawa S, Kurokawa M, Yasutomo K, Chiba S. 
Notch2 signaling is required for proper mast cell distribution and mucosal immunity in the intestine.

Blood 117:128-34 (2011)